Palestinian doc director held briefly at LAX


LOS ANGELES (AP) — Immigration officials briefly detained the Palestinian director of the Oscar-nominated documentary "5 Broken Cameras" on his way into town for Sunday's Academy Awards.


Emad Burnat says that when he arrived at Los Angeles International Airport from Turkey with his wife and 8-year-old son late Tuesday, he was told he didn't have the proper proof that he was a nominee. After about an hour of questioning, they were allowed to enter the country.


Burnat had just been in the United States two weeks earlier doing interviews alongside his co-director, Israeli activist Guy Davidi, including some with The Associated Press.


Immigration officials did not respond to requests for comment.


"5 Broken Cameras" features footage Burnat shot in his occupied West Bank village, from everyday activities with his family to protests and shootings.


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Global Update: New Polio Strains That Protect Vaccine Factory Workers





Scientists have created new strains of polio intended to protect workers in factories that make polio vaccine. The new strains have the same ability to invoke an immune reaction as the live viruses now used to make vaccine do, but there is virtually no risk anyone will get polio if one of the new strains somehow escapes.




The research team, at the State University of New York at Stony Brook, is led by Eckard A. F. Wimmer, a molecular geneticist who made headlines in 1991 when he synthesized polio virus in the lab from its chemical components, the first time a virus had been made outside of living cells.


The world is very close to eliminating polio, which is now endemic to only three countries: Afghanistan, Nigeria and Pakistan. But to be sure the disease is gone, children will have to be vaccinated for several years after the last detected case.


Currently, factories making the injectable Salk vaccine used in the United States and Europe start with the dangerous wild-type viruses known as Types 1, 2 and 3. After growing a large batch, vaccine makers “kill” the virus with formaldehyde and prepare it for syringes. The finished product is safe, but if the growing live viruses ever escaped “because of a leak, an explosion, an earthquake, a tsunami, a flood,” Dr. Wimmer said, “the spill could spread like wildfire.”


Right now, polio eradication depends on large sweeps by volunteers putting drops of the oral Sabin vaccine into children’s mouths. It is easy to give, and it produces better immunity because it reaches the intestines, which are lined with receptors for the virus.


The Sabin vaccine has drawbacks, however: it contains a still-live virus that was mutated long ago so that it is usually too weak to produce disease. In rare cases, it can mutate back into a dangerous form that paralyzes or kills. And the vaccine is risky in children with immune-system problems. For those reasons, the World Health Organization plans to eventually phase it out.


Once that happens, factories around the world will have to make millions more doses of the injectable version, so five years ago, the W.H.O. began looking for safer seed strains of virus.


Dr. Wimmer and colleagues took a part of the virus’s RNA that is crucial for growth, mutated it to weaken it, and inserted it in another stretch of RNA that controls how virulent the virus is. That renders the virus less lethal. “If it were to get into the brain, it doesn’t do any harm,” he said.


And, he explained, even if the virus evolved to defeat that virulence-lowering mutation, it would simultaneously cripple its own ability to reproduce.


Now Dr. Wimmer’s team is working with the Crucell vaccine company to prove that the safer strains grow well in Crucell’s proprietary human cell line. Ideally, he said, the new vaccine will eventually be mixed with others like those for measles and diphtheria, and all will be delivered together in one painless shot by a jet injector.


This article has been revised to reflect the following correction:

Correction: February 20, 2013

An earlier version of this article misstated the location of a university. It is in Stony Brook, not Stonybrook.



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Japan traces Boeing 787 problem to improper wiring, report says









Japan’s investigation into a burning lithium-ion battery aboard a Boeing 787 Dreamliner flight found it was improperly wired, according to an Associated Press report.


The country’s Transport Safety Board had been looking into the circumstances that led the All Nippon Airways flight to make an emergency landing in southwestern Japan.


All 137 passengers and crew were evacuated from the aircraft and slid down the Dreamliner's emergency slides. Video of the event captured by a passenger has been viewed worldwide.





According to the AP, the Transport Safety Board’s report said “the battery of the aircraft's auxiliary power unit was incorrectly connected to the main battery that overheated, although a protective valve would have prevented power from the APU from doing damage.”


More analysis was still needed, the report said.


The announcement was the latest update of the safety investigation into the 787 after the U.S. Federal Aviation Administration grounded the aircraft Jan. 16 following two incidents within two weeks involving the batteries.


The technology was also implicated in a Jan. 6 fire aboard a parked 787 in Boston operated by Japan Airlines. The National Transportation Safety Board is still probing the root cause of the event, but said this month that investigators had found a short circuit in one of the aircraft’s batteries.


Boeing has delivered 50 787s to eight airlines worldwide. Six of the planes are owned by United Airlines -- the only U.S. carrier that has 787s in its fleet.


Boeing said that it is unable to comment on the Transportation Safety Board's findings, "as it is part of the investigation in Japan."


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Boeing 787 Dreamliner fire traced to battery cell, but questions remain





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O.C. shootings: Plumber was chased, gunned down, co-worker says









One of the victims in Tuesday's shootings and carjackings in Orange County was identified by co-workers as a plumber who was working at a hotel construction site in Tustin near the scene of one of the fatal confrontations. Another plumber at the site was shot and wounded as he apparently attempted to aid his co-worker.

Three people have been reported killed and at least two seriously injured in the morning's violence, which apparently started in a residential compound in Ladera Ranch and ended in a center median in Orange where a man believed to have been the assailant got out of a vehicle and shot himself to death with a shotgun, authorities said.






Employees at the construction site in Tustin said a plumber working at the under-construction Fairfield Inn on Edinger Avenue near the 55 Freeway was chased and killed by the gunman.

The man was shot at an overflow parking lot, across the street from the construction project, workers said. Workers said the victim was one of 70 to 80 people finishing off the hotel and a neighboring Marriott Residence Inn.

Tom Van Schindel, a project superintendent at the site, said he heard the gunfire but -- given the noise in the construction zone -- wasn't initially certain what it was.

But he said another plumber later told police that he heard some noise and glanced through a third-story window at the Fairfield. That man spotted the victim running across the overflow parking lot.

Van Schindel said the second man told police that he scampered down from the third story, jumped in his white utility vehicle and sped across the street to come to the aid of his fellow plumber.

The would-be rescuer, Van Schindel said, was apparently shot once and wounded when he reached the overflow parking lot. The other plumber, he said he was told, was killed.

An employee with KBL Plumbing in Rancho Cucamonga, where the two men were said to be employed, said one of its workers was killed and one was injured Tuesday. There were no further details.

The suspect's alleged series of killings appeared to begin early Tuesday at a home in Ladera Ranch, where Orange County Sheriff's Department spokesman Jim Amormino said deputies found a woman shot to death about 4:45 a.m.
Deputies were called to the house on Red Leaf Lane when someone inside reported a shooting, Amormino said. It was unclear whether anyone else was home at the time, but no other injuries were reported.

The suspect, initially described as a man in his 20s, fled the area in an SUV to Tustin, where "multiple incidents" occurred in the city and near the Santa Ana border, Amormino said.

"There's a lot to sort out," he told The Times.



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McCartney, Mumford top eclectic Bonnaroo lineup


NASHVILLE, Tenn. (AP) — There will be a British invasion of the main stage at Bonnaroo this year.


Paul McCartney and Mumford & Sons are among the headliners for the 2013 Bonnaroo Music & Arts Festival in Manchester, Tenn.


The four-day festival, held on a rural 700-acre farm, always features an eclectic roster, but the June 13-16 event is even more varied than usual.


Returnees Tom Petty & the Heartbreakers also hold down a headliner spot. Then things get a little crazy with R&B star R. Kelly, alternative queen Bjork and Wu-Tang Clan celebrating its 20th anniversary. Wilco, Pretty Lights, The Lumineers, The National, The xx, Kendrick Lamar, A$AP Rocky, Nas and ZZ Top also top the list announced Tuesday by "Weird Al" Yankovic via Bonnaroo's YouTube channel.


Tickets go on sale at noon EST on Saturday.


McCartney, the former Beatle and recent frontman of Sirvana, will be making his first appearance at the event.


Mumford & Sons, fresh off its album of the year win at the Grammy Awards, return to Bonnaroo after a memorable 2011 second-stage performance that stretched more than an hour, drew friends Old Crow Medicine Show and had fans hanging off fences to get a better view.


Other top-of-the-list performers include Macklemore & Ryan Lewis, Animal Collective, Daniel Tosh, David Byrne & St. Vincent, Passion Pit and Grizzly Bear.


The festival hosts more than 120 acts. More will be announced later.


There are a few curiosities on the list. Glam-punk Billy Idol and Odd Future member and mystery man Earl Sweatshirt are scheduled to perform. Jim James will host a Soul SuperJam with John Oates, Zigaboo Modeliste of the Meters and the Preservation Hall Jazz Band.


Fans of roots rock, Americana and folk-leaning acoustic music will have more than Mumford and The Lumineers to focus on. Also scheduled to perform are Dwight Yoakam, Jason Isbell & The 400 Unit, John Fullbright, Of Monsters and Men, Calexico, JD McPherson, Father John Misty and The Tallest Man on Earth.


___


Follow AP Music Writer Chris Talbott: http://twitter.com/Chris_Talbott.


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Personal Health: Health Effects of Smoking for Women

The title of a recent report on smoking and health might well have paraphrased the popular ad campaign for Virginia Slims, introduced in 1968 by Philip Morris and aimed at young professional women: “You’ve come a long way, baby.”

Today that slogan should include: “. . . toward a shorter life.” Ten years shorter, in fact.

The new report is one of two rather shocking analyses of the hazards of smoking and the benefits of quitting published last month in The New England Journal of Medicine. The data show that “women who smoke like men die like men who smoke,” Dr. Steven A. Schroeder, a professor of health and health care at the University of California, San Francisco, wrote in an accompanying editorial.

That was not always the case. Half a century ago, the risk of death from lung cancer among men who smoked was five times higher than that among women smokers. But by the first decade of this century, that risk had equalized: for both men and women who smoked, the risk of death from lung cancer was 25 times greater than for nonsmokers, Dr. Michael J. Thun of the American Cancer Society and his colleagues reported.

Today, women who smoke are even more likely than men who smoke to die of lung cancer. According to a second study in the same journal, women smokers face a 17.8 times greater risk of dying of lung cancer, than women who do not smoke; men who smoke are at 14.6 times greater risk to die of lung cancer than men who don’t. Women who smoke now face a risk of death from lung cancer that is 50 percent higher than the estimates reported in the 1980s, according to Dr. Prabhat Jha of the Center for Global Health Research in Toronto and his colleagues.

After controlling for age, body weight, education level and alcohol use, the new analysis found something else: men and women who continue to smoke die on average more than 10 years sooner than those who never smoked.

Dramatic progress has been made in reducing the prevalence of smoking, which has fallen in the United States from 42 percent of adults in 1965 (the year after the first surgeon general’s report on smoking and health) to 19 percent in 2010. Yet smoking still results in nearly 200,000 deaths a year among people 35 to 69 years old in this country. A quarter of all deaths in this age group would not occur if smokers had the same risk of death as nonsmokers.

The risks are even greater among men 55 to 74 and women 60 to 74. More than two-thirds of all deaths among current smokers in these age groups are related to smoking. Over all, the death rate from all causes combined in these age groups “is now at least three times as high among current smokers as among those who have never smoked,” Dr. Thun’s team found.

While lung cancer is the most infamous hazard linked to smoking, the habit also raises the risk of death from heart disease, stroke, pulmonary disease and other cancers, including breast cancer.

Furthermore, changes in how cigarettes are manufactured may have increased the dangers of smoking. The use of perforated filters, tobacco blends that are less irritating, and paper that is more porous made it easier to inhale smoke and encouraged deeper inhalation to achieve satisfying blood levels of nicotine.

The result of deeper inhalation, Dr. Thun’s report suggests, has been an increased risk of chronic obstructive pulmonary disease, or C.O.P.D., and a shift in the kind of lung cancer linked to smoking. Among nonsmokers, the risk of death from C.O.P.D. has declined by 45 percent in men and has remained stable in women, but the death rate has more than doubled among smokers.

But there is good news, too: it’s never too late to reap the benefits of quitting. The younger you are when you stop smoking, the greater your chances of living a long and healthy life, according to the findings of Dr. Jha’s international team.

The team analyzed smoking and smoking-cessation histories of 113,752 women and 88,496 men 25 and older and linked them to causes of deaths in these groups through 2006.

Those who quit smoking by age 34 lived 10 years longer on average than those who continued to smoke, giving them a life expectancy comparable to people who never smoked. Smokers who quit between ages 35 and 44 lived nine years longer, and those who quit between 45 and 54 lived six years longer. Even quitting smoking between ages 55 and 64 resulted in a four-year gain in life expectancy.

The researchers emphasized, however, that the numbers do not mean it is safe to smoke until age 40 and then stop. Former smokers who quit by 40 still experienced a 20 percent greater risk of death than nonsmokers. About one in six former smokers who died before the age of 80 would not have died so young if he or she had never smoked, they reported.

Dr. Schroeder believes we can do a lot better to reduce the prevalence of smoking with the tools currently in hand if government agencies, medical insurers and the public cooperate.

Unlike the races, ribbons and fund-raisers for breast cancer, “there’s no public face for lung cancer, even though it kills more women than breast cancer does,” Dr. Schroeder said in an interview. Lung cancer is stigmatized as a disease people bring on themselves, even though many older victims were hooked on nicotine in the 1940s and 1950s, when little was known about the hazards of smoking and doctors appeared in ads assuring the public it was safe to smoke.

Raising taxes on cigarettes can help. The states with the highest prevalence of smoking have the lowest tax rates on cigarettes, Dr. Schroeder said. Also helpful would be prohibiting smoking in more public places like parks and beaches. Some states have criminalized smoking in cars when children are present.

More “countermarketing” of cigarettes is needed, he said, including antismoking public service ads on television and dramatic health warnings on cigarette packs, as is now done in Australia. But two American courts have ruled that the proposed label warnings infringed on the tobacco industry’s right to free speech.

Health insurers, both private and government, could broaden their coverage of stop-smoking aids and better publicize telephone quit lines, and doctors “should do more to stimulate quit attempts,” Dr. Schroeder said.

As Nicola Roxon, a former Australian health minister, put it, “We are killing people by not acting.”

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Samuel Adams beer now in a can









Add Samuel Adams to the growing list of beers available in cans.


The Boston Beer Co. said it will start selling its popular Samuel Adams Boston Lager in cans for the first time this summer, the Associated Press reports.


The move will allow beer fans to take the popular lager places where glass bottles may not be allowed, such as pools, parks, beaches and sporting events.





Once considered to impair the taste of fine beers, cans are now used by more than 180 craft breweries, according to the website ontaponline.com.  


Brewers have long been using a thin, plastic lining inside cans to reduce the dreaded metallic taste.


There are other benefits: Brewers appreciate that cans are lighter and more compact than bottles, reducing shipping costs, and they won’t shatter into a thousand pieces if dropped, ontaponline.com noted.


Sierra Nevada Brewing Co. in Chico, Calif., already sells its Torpedo Extra IPA in cans. Redhook Ale Brewery in Woodinville, Wash., recently started offering Long Hammer IPA in cans.


The Boston Beer Co. says cans of Samuel Adams lager will be available in 12-packs nationwide by early summer. It suggests a price range of $14.99 to $17.99.


Shares of Boston Beer Co. were up $4.19, or 2.8%, in trading Tuesday morning.


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Follow Stuart Pfeifer on Twitter







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Jerry Buss dies at 80; Lakers owner brought 'Showtime' success to L.A.

Longtime Lakers owner Jerry Buss has died at the age of 80. Last week, it was revealed that he was hospitalized with an undisclosed form of cancer.









When Jerry Buss bought the Lakers in 1979, he wanted to build a championship team. But that wasn't all.


The new owner gave courtside seats to movie stars. He hired pretty women to dance during timeouts. He spent freely on big stars and encouraged a fast-paced, exuberant style of play.


As the Lakers sprinted to one NBA title after another, Buss cut an audacious figure in the stands, an aging playboy in blue jeans, often with a younger woman by his side.








PHOTOS: Jerry Buss through the years


"I really tried to create a Laker image, a distinct identity," he once said. "I think we've been successful. I mean, the Lakers are pretty damn Hollywood."


Buss died Monday of complications of cancer at Cedars-Sinai Medical Center in Los Angeles, according to his longtime spokesman, Bob Steiner. Buss was 80.


Lakers fans will remember Buss for bringing extraordinary success — 10 championships in three-plus decades — but equally important to his legacy was a sense of showmanship that transformed pro basketball from sport to spectacle.


Live discussion at 10:30: The legacy of Jerry Buss


"Jerry Buss helped set the league on the course it is on today," NBA Commissioner David Stern said. "Remember, he showed us it was about 'Showtime,' the notion that an arena can become the focal point for not just basketball, but entertainment. He made it the place to see and be seen."


His teams featured the likes of Kareem Abdul-Jabbar, Magic Johnson, Kobe Bryant, Shaquille O'Neal and Dwight Howard. He was also smart enough to hire Hall of Fame-caliber coaches in Pat Riley and Phil Jackson.


"I've worked hard and been lucky," Buss said. "With the combination of the two, I've accomplished everything I ever set out to do."


A Depression-era baby, Jerry Hatten Buss was born in Salt Lake City on Jan. 27, 1933, although some sources cite 1934 as his birth year. His parents, Lydus and Jessie Buss, divorced when he was an infant.


His mother struggled to make ends meet as a waitress in tiny Evanston, Wyo., and Buss remembered standing in food lines in the bitter cold. They moved to Southern California when he was 9, but within a few years she remarried and her second husband took the family back to Wyoming.


His stepfather, Cecil Brown, was, as Buss put it, "very tight-fisted." Brown made his living as a plumber and expected his children (one from a previous marriage, another son and a daughter with Jessie) to help.


TIMELINE: Jerry Buss' path


This work included digging ditches in the cold. Buss preferred bell hopping at a local hotel and running a mail-order stamp-collecting business that he started at age 13.


Leaving high school a year early, he worked on the railroad, pumping a hand-driven car up and down the line to make repairs. The job lasted just three months.


Until then, Buss had never much liked academics. But he returned to school and, with a science teacher's encouragement, did well enough to earn a science scholarship to the University of Wyoming.


Before graduating with a bachelor's degree in chemistry, when he was 19 he married a coed named JoAnn Mueller and they would eventually have four children: John, Jim, Jeanie and Janie.


The couple moved to Southern California in 1953 when USC gave Buss a scholarship for graduate school. He earned a doctorate in physical chemistry in 1957. The degree brought him great pride — Lakers employees always called him "Dr. Buss."





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McCready's ex: Anyone close could see it coming


HEBER SPRINGS, Ark. (AP) — Mindy McCready threatened to kill herself after losing custody of her sons earlier this month, yet she was allowed to leave a court-ordered drug rehabilitation program days before she apparently killed herself, her ex-boyfriend said Monday.


Billy McKnight, who was in a long, rocky relationship with McCready and who is the father of her oldest child, Zander, said the 37-year-old mother of two stayed in the in-patient substance abuse treatment center for about 18 hours before being allowed to walk free.


Authorities say McCready died in an apparent suicide Sunday at her home in Heber Springs, a vacation community about 65 miles north of Little Rock. Sheriff Marty Moss said McCready was found dead on the front porch where her boyfriend, musician David Wilson, died last month of a gunshot wound to the head. Investigators are investigating his death as a suicide, but haven't yet determined the his cause of death.


McKnight, speaking to The Associated Press phone from Tampa, Fla., said McCready and Wilson had actually gotten engaged. He wondered how she was allowed to go free, given all the turmoil in her life.


"That was a big mistake on the part of whoever released her," McKnight said. "... She was in a terrible state of mind. She doesn't perform any more. She wasn't working. She has two kids and her fiance was just killed. There's no way she should be out by herself in a lonely house with nothing but booze and pills. That was a really, really bad mistake, and the end result is tragic."


Neighbors reported hearing two shots Sunday afternoon when they called the Cleburne County Sheriff's Office. Authorities found Wilson's dog dead next to McCready's body.


"Based on what we have found at the scene at this time, we do believe that she took the life of the dog that we are being told by family members belonged to Mr. Wilson before she took her own life," Sheriff Marty Moss said.


The sheriff confirmed McCready's two sons remained in foster care where they were at the time of her death. McKnight says he's working with authorities to get custody of his son, Zander, and was not privy to what's happening with infant boy Zayne, who was born to McCready and Wilson last year.


McCready's sons were put in foster care and she was ordered into rehab earlier this month after McCready's father expressed concern. He told a judge his daughter had stopped taking care of herself and her children after Wilson's death and she was abusing alcohol and prescription drugs.


Moss said he expects McCready's official cause of death will be released soon, but that "all indicators" point to a suicide. Her body has been sent to the state crime lab for autopsy.


McCready attempted suicide at least three times previously and her fragile state of mind was always a concern to family and friends who cared for her.


"This didn't come as a surprise, although shocking," McKnight said. "She was bitter. She was bitter at the world and she was bitter at herself, and she could just never shake it. She could never beat it.


___


AP writer Jeannie Nuss in Arkansas contributed to this report. Music Writer Chris Talbott wrote from Nashville, Tenn.


___


Follow AP Music Writer Chris Talbott: http://twitter.com/Chris_Talbott


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Well: Dangers of Too Much Calcium

Calcium is an important nutrient for bone health, but new research suggests that older women who take large amounts may be at increased risk of heart disease and death.

Swedish researchers followed 61,433 women born between 1914 and 1948 for an average of 19 years, confirming causes of death with a Swedish government registry. The investigators also used questionnaires to record the women’s food and calcium supplement intake.

After controlling for physical activity, education, smoking, alcohol and other dietary factors, they found that women who consumed 1,400 milligrams or more of calcium a day had more than double the risk of death from heart disease, compared with those with intakes between 600 and 1,000 milligrams. These women also had a 49 percent higher rate of death from cardiovascular disease, and a 40 percent higher risk of death from any cause.

The study, published last week online in BMJ, found the increased risk only in women who consumed the most calcium — there was no gradually increased risk with gradually increased calcium intake.

The authors noted that calcium can increase blood levels of a protein associated with higher risk for cardiovascular disease.

“If you have a normal diet, you don’t need to take calcium supplements,” said the lead author, Dr. Karl MichaĆ«lsson, a professor and orthopedic surgeon at Uppsala University in Sweden. “Calcium supplements are useful if you have a very low intake of calcium, but few women have such a low intake.”

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