Dark Horse, Wood start new 'Star Wars' comic

PHILADELPHIA (AP) — There's excitement brewing for fans of the original "Star Wars" trilogy.

Writer Brian Wood and Dark Horse Comics began a new monthly series Wednesday that focuses on Luke Skywalker, Princess Leia Organa, Han Solo and Chewbacca, along with R2D2 and C3P0, as they seek to establish a foothold for the rebellion in the aftermath of the Death Star's destruction.

Wood, whose previous comics include the acclaimed "DMZ" and "Northlanders" at Vertigo and the ongoing "The Massive" at Dark Horse, called the new series about the classic "Star Wars" characters the only such series he could write.

"I know the original trilogy best," he explained, noting that George Lucas' creation has spawned its own universe of expanded characters, books, comics and more.

Disney has already announced plans to revive the "Star Wars" franchise after the events of "Return of the Jedi" in 2015. Milwaukie, Ore.-based Dark Horse has been publishing "Star Wars" comics for more than 20 years.

Woods called the new series — illustrated by Carlos D'Anda — a way to examine the events that transpired between the end of the first film, "Star Wars: A New Hope" and the second film, "The Empire Strikes Back," by detailing the next, furtive steps for the rebellion and the Empire's efforts to stop it from spreading.

"The basic approach is sort of how everybody, including the Empire, is kind of reeling from that battle in various different ways," Wood said. "The rebellion is in need of a home base, Darth Vader is dealing with serious disapproval from the Emperor for having failed to stop the Death Star's destruction — he's actually been demoted!"

Leia has lost her home world. Luke lost his family. Han and Chewie have seen their smuggling business hurt by their association with the rebels.

"Everyone has suffered enormous losses," Wood said.

Wood said the challenge for the series is keeping track of all the story possibilities, given the established mythology of the "Star Wars" universe and the sheer number of characters.

"It's a big cast! The droids, Ben Kenobi is there, all of the Empire, too. It's a very large cast so that's kind of a tricky thing," he said.

And most readers already know what happened to the characters, good and bad.

"It's writing the story knowing what the audience knows but what the characters don't. Obviously, Luke and Leia don't know they're related — I can't ignore that," Wood said.

"It's a very enjoyable challenge walking that line," he said.

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Matt Moore can be reached at http://www.twitter.com/mattmooreap

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Online:

Dark Horse: http://bit.ly/RGkqMu

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Pap Test May Prove Useful at Detecting More Types of Cancer, Study Suggests

The Pap test, which has prevented countless deaths from cervical cancer, may eventually help to detect cancers of the uterus and ovaries as well, a new study suggests.

For the first time, researchers have found genetic material from uterine or ovarian cancers in Pap smears, meaning that it may become possible to detect three diseases with just one routine test.

But the research is early, years away from being used in medical practice, and there are caveats. The women studied were already known to have cancer, and while the Pap test found 100 percent of the uterine cancers, it detected only 41 percent of the ovarian cancers. And the approach has not yet been tried in women who appear healthy, to determine whether it can find early signs of uterine or ovarian cancer.

On the other hand, even a 41 percent detection rate would be better than the status quo in ovarian cancer, particularly if the detection extends to early stages. The disease is usually advanced by the time it is found, and survival is poor. About 22,280 new cases were expected in the United States in 2012, and 15,500 deaths. Improved tests are urgently needed.

Uterine cancer has a better prognosis, but still kills around 8,000 women a year in the United States.

These innovative applications of the Pap test are part of a new era in which advances in genetics are being applied to the detection of a wide variety of cancers or precancerous conditions. Scientists are learning to find minute bits of mutant DNA in tissue samples or bodily fluids that may signal the presence of hidden or incipient cancers. Ideally, the new techniques would find the abnormalities early enough to cure the disease or even prevent it entirely. But it is too soon to tell.

“Is this the harbinger of things to come? I would answer yes,” said Dr. Bert Vogelstein, director of the Ludwig Center for Cancer Genetics and Therapeutics at Johns Hopkins University, and a senior author of a report on the Pap test study published on Wednesday in the journal Science Translational Medicine. He said the genomes of more than 50 types of tumors had been sequenced, and researchers were trying to take advantage of the information.

Similar studies are under way or are being considered to look for mutant DNA in blood, stool, urine and sputum, both to detect cancer and also to monitor the response to treatment in people who already have the disease.

But researchers warn that such tests, used for screening, can be a double-edged sword if they give false positive results that send patients down a rabbit hole of invasive tests and needless treatments. Even a test that finds only real cancers may be unable to tell aggressive, dangerous ones apart from indolent ones that might never do any harm, leaving patients to decide whether to watch and wait or to go through surgery, chemotherapy and radiation with all the associated risks and side effects.

“Will they start recovering mutations that are not cancer-related?” asked Dr. Christopher P. Crum, a professor at Harvard Medical School who was not involved in the research.

But he also called the study a “great proof of principle,” and said, “Any whisper of hope to women who suffer from endometrial or ovarian cancer would be most welcome.”

DNA testing is already performed on samples from Pap tests, to look for the human papillomavirus, or HPV, which causes cervical cancer. Dr. Vogelstein and his team decided to try DNA testing for cancer. They theorized that cells or DNA shed from cancers of the ovaries and the uterine lining, or endometrium, might reach the cervix and turn up in Pap smears.

The team picked common mutations found in these cancers, and looked for them in tumor samples from 24 women with endometrial cancer and 22 with ovarian cancer. All the cancers had one or more of the common mutations.

Then, the researchers performed Pap tests on the same women, and looked for the same DNA mutations in the Pap specimens. They found the mutations in 100 percent of the women with endometrial cancer, but in only 9 of the 22 with ovarian cancer. The test identified two of the four ovarian cancers that had been diagnosed at an early stage.

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Wall Street gains as earnings flow in; Alcoa up

Stocks rose on Wall Street Wednesday after U.S. corporate earnings reports got off to a good start.

The Dow Jones industrial average rose 86 points to 13,415 as of noon EST. The Dow is coming off of two days of losses.

The Standard & Poor's 500 index gained six points to 1,463 and the Nasdaq composite rose 17 points to 3,109.

Stocks, having rallied after a last-minute resolution stopped the U.S. going from over the “fiscal cliff,” are facing their first challenge of the year as companies start to report their earnings for the fourth quarter of 2012. Throughout last year, analysts had cut their outlook for earnings growth in the period and now expect them to rise by 3.21 percent, according to data from S&P Capital IQ.

“Maybe earnings expectations were a little too low,” said Ryan Detrick, a strategist at Schaeffer's Investment Research. “You don't need to have great earnings, you just need to beat those expectations” for stocks to rally, Detrick said.

Alcoa predicted rising demand for aluminum this year as the aerospace industry gains strength. Late Tuesday the company reported fourth-quarter revenue that beat analysts' estimates. Investors pay close attention to Alcoa's results and forecasts because the aluminum it makes is used in so many industries including construction and manufacturing.

Alcoa's stock rose 8 cents to $9.18.

Consumer products maker Helen of Troy, whose brands include Dr. Scholl's, Vicks and Fabreze, rose 89 cents to $34.42 after reporting a 15 percent increase in net income. Agricultural products giant Monsanto gained 84 cents to $99.34 after it said that its profit nearly tripled in the first fiscal quarter as sales of its biotech corn seeds expanded in Latin America.

The yield on the 10-year Treasury note was unchanged at 1.87 percent.

Among other stocks making big moves:

— Wireless network operator Clearwire jumped 22 cents to $3.14 after Dish network made an unsolicited offer to buy the company, which has already agreed to sell itself to Sprint. Dish rose $1.17 to $37.14 and Sprint fell 8 cents to $5.89.

— Online education company Apollo Group plunged 10 percent after reporting a sharp decline in fall-term student sign-ups at the University of Phoenix. The stock fell $2.04 to $18.88.

— Seagate Technology, a maker of hard-disk drives, jumped $1.52 to $32.91 after predicting revenue for its fiscal second quarter that topped Wall Street expectations late Tuesday.

— Bank of America fell 29 cents to $11.69 after Credit Suisse analysts lowered their outlook on the lender to “neutral” for “outperform,” saying the current stock price overestimates the improvement in cost reduction that the bank can achieve this year.

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Testimony about Colorado massacre resumes in James Holmes hearing

More emotional testimony was expected at a hearing on the Aurora movie theater massacre, as prosecutors continued to lay out their case against the defendant, James Holmes.

CENTENNIAL, Colo. — Vivid testimony about the movie theater massacre that shocked a nation extended into a second day as a preliminary hearing for James E. Holmes resumed Tuesday.

Prosecutors continued to lay out their case against Holmes, 25, accused of killing 12 people and injuring about 70 during a shooting rampage on July 20 in a suburban cinema. At issue in the proceeding, expected to last a week, is whether there is a sufficient case to go to trial.

In the first day of testimony Monday, law enforcement officials described the bloody shooting scene and heartbreaking rescue attempts to bring the gravely wounded to treatment.

PHOTOS: Colorado movie theater shooting

The prosecution has been trying to show that Holmes acted deliberately while the defense in cross-examination has focused on how the former neuroscience graduate student appeared emotionally detached, bolstering their expected insanity presentation.

Throughout, Holmes has sat impassive, while some of the victims' relatives have wept during the more graphic testimony.

On Tuesday, the atmosphere at the Arapahoe County Court House contained less of the frenzy that marked the first day. Yet the proceedings come as the debate over gun control has heated up in the wake of the attack last month in Newtown, Conn., in which 20 children and six adults were killed by a lone gunman who invaded the Sandy Hook Elementary School. The gunman first killed his mother in their home and ended his shooting spree by killing himself.

WHO THEY WERE: Aurora theater shooting

Tuesday’s testimony also comes as the nation commemorates the second anniversary of the Tucson shooting where six died and 13 were injured when gunman Jared Lee Loughner opened fire in a supermarket parking lot where former Rep. Gabrielle Giffords was holding a meet-and-greet with her constituents. Tucson, which has had events for several days, will mark the exact time of the shooting with the ringing of bells across the city at the moment of the morning attack.

Giffords, who went through a painful recovery and rehabilitation for gun wounds to the head, has become a spokeswoman for greater gun control. She and her husband, former astronaut Mark Kelly, announced they would raise money to support gun control efforts. The pair visited Newtown last week.

On Monday, Aurora police testified about the horrors they found in the theater, including blood-soaked aisles and walls, crumpled bodies, and scores of spent shell casings.

TIMELINE: U.S. mass shootings

The prosecution also showed surveillance video of Holmes entering the theater complex just past midnight. He had purchased his ticket 12 days earlier. The chilling, soundless video shows Holmes redeeming his ticket at a kiosk, giving it to a ticket taker, then lingering near the concession stand for a few minutes before turning toward Theater 9, where the Batman movie, “The Dark Knight Rises” was playing.

Prosecutors have yet to announce whether they will seek the death penalty.

ALSO:

Supreme Court rejects challenge to Obama stem cell policy

Chicago man fatally poisoned a month after hitting lotto jackpot

Alabama police: High school white supremacist planned bomb attack

Deam reported from Centennial, Colo.; Muskal reported from Los Angeles. 

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Fox: Passion, disagreements with new 'Idol' team

PASADENA, Calif. (AP) — Five minutes into their season-opening news conference and the new team at "American Idol" were having their first disagreement — about their disagreements.

Asked Tuesday whether a supposed feud between new judges Mariah Carey and Nicki Minaj was a publicity stunt, Fox network executive Mike Darnell said it was authentic. He said there was a lot of passion within the group, which also includes country star Keith Urban and returning judge Randy Jackson. He said there were also a lot of disagreements.

Carey, however, called the story "some trumped-up thing."

Minaj later called Carey one of her favorite all-time artists who has shaped a generation of singers.

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Health Spending Growth Stays Low for 3rd Straight Year

WASHINGTON — National health spending climbed to $2.7 trillion in 2011, or an average of $8,700 for every person in the country, but as a share of the economy, it remained stable for the third consecutive year, the Obama administration said Monday.

The rate of increase in health spending, 3.9 percent in 2011, was the same as in 2009 and 2010 — the lowest annual rates recorded in the 52 years the government has been collecting such data.

Federal officials could not say for sure whether the low growth in health spending represented the start of a trend or reflected the continuing effects of the recession, which crimped the economy from December 2007 to June 2009.

Kathleen Sebelius, the secretary of health and human services, said that “the statistics show how the Affordable Care Act is already making a difference,” saving money for consumers. But a report issued by the Centers for Medicare and Medicaid Services, in her department, said that the law had so far had “no discernible impact” on overall health spending.

Although some provisions of the law have taken effect, the report said, “their influence on overall health spending through 2011 was minimal.”

The recession increased unemployment, reduced the number of people with private health insurance, lowered household income and assets and therefore tended to slow health spending, said Micah B. Hartman, a statistician at the Centers for Medicare and Medicaid Services.

In the report, federal officials said that total national spending on prescription drugs and doctors’ services grew faster in 2011 than in the year before, but that spending on hospital care grew more slowly.

Medicaid spending likewise grew less quickly in 2011 than in the prior year, as states struggled with budget problems. But Medicare spending grew more rapidly, because of an increase in “the volume and intensity” of doctors’ services and a one-time increase in Medicare payments to skilled nursing homes, said the report, published in the journal Health Affairs.

National health spending grew at roughly the same pace as the overall economy, without adjusting for inflation, so its share of the economy stayed the same, at 17.9 percent in 2011, where it has been since 2009. By contrast, health spending accounted for just 13.8 percent of the economy in 2000.

Health spending grew more than 5 percent each year from 1961 to 2007. It rose at double-digit rates in some years, including every year from 1966 to 1984 and from 1988 to 1990.

The report did not forecast the effects of the new health care law on future spending. Some provisions of the law, including subsidized insurance for millions of Americans, could increase spending, officials said. But the law also trims Medicare payments to many health care providers and authorizes experiments to slow the growth of health spending.

“The jury is still out whether all the innovations we’re testing will have much impact,” said Richard S. Foster, who supervised the preparation of the report as chief actuary of the Medicare agency. “I am optimistic. There’s a lot of potential. More and more health care providers understand that the future cannot be like the past, in which health spending almost always grew faster than the gross domestic product.”

Evidence of the new emphasis can be seen in a series of articles published in The Archives of Internal Medicine, now known as JAMA Internal Medicine, under the title “Less Is More.” The series highlights cases in which “the overuse of medical care may result in harm and in which less care is likely to result in better health.”

Total spending for doctors’ services rose 3.6 percent in 2011, to $436 billion, while spending for hospital care increased 4.3 percent, to $850.6 billion.

Spending on prescription drugs at retail stores reached $263 billion in 2011, up 2.9 percent from 2010, when growth was just four-tenths of 1 percent. The latest increase was still well below the average increase of 7.8 percent a year from 2000 to 2010.

Federal officials said the increase in 2011 resulted partly from rapid growth in prices for brand-name drugs.

Prices for specialty drugs, typically prescribed by medical specialists for chronic conditions, have increased at double-digit rates in recent years, the government said. In addition, spending on new brand-name drugs — those brought to market in the previous two years — more than doubled from 2010 to 2011, driven by an increase in the number of new medicines.

“In 2011,” the report said, “spending for private health insurance premiums increased 3.8 percent, as did spending for benefits. Out-of-pocket spending by consumers increased 2.8 percent in 2011, accelerating from 2.1 percent in 2010 but still slower than the average annual growth rate of 4.7 percent” from 2002 to 2008.

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Disneyland takes photos of guests to crack down on ticket abuse

Workers at Disneyland and Disney California Adventure Park took photos of visitors entering the parks Tuesday as part of a new effort to crack down on abuse of multi-day tickets.

The process of photographing guests--including children--delayed visitors getting into the park by about 45 minutes, according to park-goers.

"They delayed literally thousands of people in line to do this process," said Bob Shoberg, a San Jose resident who visited Disneyland with his wife, daughters, in-laws and grandchildren.

Disneyland officials denied that guests suffered significant delays.

Disney has long struggled to stop several businesses in Anaheim that buy multi-day park passes and then "lease" or "rent" the passes to visitors for individual days.

The scenario works like this: Ticket brokers might, for example, buy a three-day "park hopper" pass for $205 and rent the ticket to guests for $85 a day. The seller makes a profit of $50 and the guests, who would otherwise pay $125 for a one-day "park hopper" ticket, saves $40.

Disneyland policy prohibits visitors from sharing multi-day passes but the practice does not violate local laws.

To put a stop to the practice, Disneyland workers began Tuesday to photograph visitors who are using a multi-day pass for the first time, said park spokeswoman Suzi Brown.

When the pass is used a second time, Disneyland workers at the park turnstiles will see a photo of the guest pop up on a screen, she said. If the person at the turnstile is not the person shown on the photo, Brown said the guest won't be allowed to use the ticket.

The photo process involved a "very small percentage of guests" and did not cause a significant delay, she said.

ALSO:

After dark, the dirty work at Disneyland begins

Disneyland's Big Thunder Mountain Railroad to close for upgrades

Angry Birds Land set to debut at European theme park

Follow Hugo Martin on Twitter at @hugomartin

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Ten banks to pay $8.5 billion to settle foreclosure abuse review

WASHINGTON -- Ten of the nation's largest mortgage servicers have agreed to an $8.5-billion settlement with federal regulators to end a review of foreclosure abuses.

The settlement, announced Monday, involved some of the biggest names in the financial industry, including Bank of America Corp., Wells Fargo & Co., JPMorgan Chase & Co. and Citigroup Inc..

They agreed to pay a total of $3.3 billion to more than 3.8 million borrowers whose homes were in foreclosure in 2009 and 2010, according to the Federal Reserve and the Office of the Comptroller of the Currency. Borrowers could receive as much as $125,000, depending on the type of problems with their foreclosures.

In addition, the banks agreed to provide $5.2 billion in other assistance to those borrowers, including modifications to their mortgages or having judgments against them forgiven.

The other servicers participating in the settlement are Aurora Loan Services, MetLife Bank, PNC Financial Services, Sovereign Bank, SunTrust Banks and U.S. Bancorp. Four smaller servicers whose foreclosure practices have been under review did not sign on to Monday's settlement.

Under the original plan devised by the comptroller and the Federal Reserve in April 2011, 4.4 million Americans whose homes were in foreclosure proceedings in 2009 and 2010 could request a free review. Only about half a million have done so.

Regulators decided to stop the reviews in exchange for the cash payments and assistance.

Borrowers who requested reviews would get bigger cash payments. Those that did not would get a few hundred dollars. Those who requested reviews would get bigger payments.

"When we began the Independent Foreclosure Review, the OCC pledged to fix what was broken, identify who was harmed and compensate them for that injury," said Comptroller of the Currency Thomas J. Curry. 

"While today's announcement represents a significant change in direction," he continued, "it meets those original objectives by ensuring that consumers are the ones who will benefit and that they will benefit more quickly and in a more direct manner."

Curry said that although regulators have "have learned a great deal from the reviews ... it has become clear that carrying the process through to its conclusion would divert money away from the impacted homeowners" and delay compensation to the borrowers.

Rep. Elijah E. Cummings (D-Md.), criticized the decision by regulators to reach a settlement with the mortgage servicers. 

"I am deeply disappointed that the OCC and the Federal Reserve finalized this settlement and effectively terminated the Independent Foreclosure Review process before providing Congress answers to serious questions about how this settlement amount was determined, who these funds will go to, and what will happen to other families who were abused by these mortgage servicing companies, but have not yet had their cases reviewed," Cummings said.

He said he didn't know "know what the rush was to make this settlement without answering these key questions" and that he had "serious concerns that this settlement may allow banks to skirt what they owe and sweep past abuses under the rug without determining the full harm borrowers have suffered."

 ALSO:

Investors bet BofA can begin to focus on expansion

$10-billion settlement of foreclosure abuse cases said to be near

Bank of America to pay Fannie Mae $10 billion in loan settlement

Follow Jim Puzzanghera on Twitter and Google+.

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Jimmy Kimmel moves to late-night's sweet spot

LOS ANGELES (AP) — During production of his final post-midnight show, Jimmy Kimmel's studio audience waited patiently while he taped a string of promotional spots.

"Hey, Denver: You, me, now at 10:35. Let's not be weird about this," the host quipped to the camera in his Hollywood Boulevard studio.

"This will be good for us," Kimmel said earnestly in another local station promo.

The message in each spot — whether "Jimmy Kimmel Live" is on at 11:35 p.m. in the East and West or earlier elsewhere — is that Kimmel will be playing in the same league as veterans Jay Leno and David Letterman, starting Tuesday with guests Jennifer Aniston and No Doubt.

The message Kimmel delivered to a recent teleconference was equally concise: He won't be changing his style for the move, pushing aside conventional wisdom that edgier late-night humor won't play in Peoria or elsewhere before the clock strikes 12.

It's "Jimmy Kimmel Live," after all, that has given the world such brashly funny videos as the Matt Damon-Sarah Silverman musical romp with bleep-worthy lyrics.

"There's this idea that you need to broaden the show or make it ... more wholesome or something like that. And I think that's a little bit out-of-date, that perception," Kimmel told reporters.

"I guess only time will tell," he added, in his typically low-key delivery.

Just as with Kimmel's promised approach to the most coveted time period in late-night, ABC is taking a bold step by swapping "Nightline" with his show. The news program, offering viewers a non-talk show option, has been the period's ratings leader.

But the network likely won't be sweating the early returns, according to analyst Brad Adgate of Horizon Media. He says putting Kimmel into the pre-midnight pocket, when more viewers are still up and watching, is a strategy aimed at an inevitable future.

"Leno and Letterman aren't going to be doing this forever," Adgate said, and ABC gives him a head start on establishing himself by putting him on now.

"This is something you may scratch your head at now, but in five years from now he's the incumbent and the leader" in the time period, the analyst said.

Long-term schemes, of course, don't always pan out. Despite anointing Conan O'Brien as its new "Tonight" host five years before he made the move in 2009, NBC ended up with a mess on its hands that saw O'Brien bolt to TBS and Leno retake "Tonight" in 2010 after his short-lived prime-time series.

Whether Kimmel gets a jump on his opponents-to-be — with Jimmy Fallon the expected pick for "Tonight" — being the late-night ruler is a far different proposition than in Johnny Carson's day. The "Tonight" institution, operating virtually unopposed, could average a nightly audience of as much as 15 million.

That's unimaginable in today's fragmented TV world. Leno claims the top talk-show spot with some 3.5 million average viewers, followed by Letterman on CBS with 2.8 million. "Jimmy Kimmel Live" was drawing under 2 million nightly viewers at 12:05 Eastern but, according to Nielsen Co. ratings, finished up 2012 with a 10-year viewership high.

The demographics also have changed, with more advertiser-favored young viewers gravitating to cable options such as Adult Swim or Comedy Central and increasingly likely to catch up online with the best moments of network late-night.

But the 11:35 p.m. East-West sweet spot remains the prize, and Kimmel may have more than the desire to succeed in mind. While he's a long-time admirer of Letterman, he's taken sharp public jabs at Leno, including blaming him for O'Brien's ill-fated tenure at "Tonight."

So Kimmel is humble about competing directly with Letterman (calling him a "legend in broadcasting" who shouldn't bat an eye at the prospect of new competition) but is throwing elbows at Leno, especially over the "Tonight" plan to get out ahead of "Jimmy Kimmel Live" by airing at 11:34 p.m. Eastern.

"Well, I think NBC has had a lot of success moving Jay Leno earlier so it makes perfect sense," he said, dryly, referring to Leno's short-lived prime-time stint. Kimmel dismissed the time-shifting as likely a brief "trick" to protect "Tonight" ratings, one that ultimately won't matter.

"This really isn't about the first month or about the first week or about the first night, it's a long-term thing," Kimmel told reporters. "If we do well the first week, I'm sure there will be a lot of press given to that. But what really matters is how you do in May, and that's when we'll really know ... where we stand."

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Online:

http://abc.go.com/

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When the Plague Came to New York

Jakob Schiller for The New York Times

Survivors Lucinda Marker and John Tull at home a decade after having the plague.

It was November 2002, little more than a year after planes had been flown into the World Trade Center and anthrax mailings had killed five Americans. New York City was still in a state of high alert for suspected terrorists.

Suddenly all eyes were on a middle-aged married couple from Santa Fe, N.M., on a brief vacation to New York, who had the remarkably ill luck to come down with the city’s first case of bubonic plague in more than a century. Television news trucks surrounded Beth Israel Medical Center North, where they had dragged themselves after being stricken in their hotel room with rampaging fevers, headaches, extreme exhaustion and mysterious balloonlike swellings.

It took just over a day for public health officials to dispel fears about bioterrorism; there had been no unusual rise in the number of very high fevers that could have suggested an attack.

It turned out that the couple, Lucinda Marker and John Tull, had been bitten by fleas infected with Yersinia pestis, the bacterium that causes plague. Their home state, New Mexico, accounts for more than half of the average seven cases of plague in the country every year. (In 2012, just one case was reported in the state.)

“It was an absolute fluke,” Ms. Marker, now 57, said during a recent visit to New York. “Just rotten luck.”

Like most people who contract the disease and are quickly treated with antibiotics, she recovered in a few days. But 10 years later, her husband is still badly scarred.

In the days after they were bitten, Mr. Tull, a burly, athletic lawyer — a former prosecutor who volunteered with search-and-rescue teams — developed septicemic plague, as the infection spread throughout his body.

His temperature rose to 104.4, his blood pressure plummeted to 78/50. His kidneys were failing, and so much clotted blood collected in his hands and feet that they turned black.

Mr. Tull was put into a medically induced coma. When he was brought out of it, nearly three months later, he found out that both his legs had been amputated below the knee to drain the deadly infection. The surgery that saved his life radically changed it, but did not dampen his resilient spirit.

Even before he was released from the hospital to begin a long rehabilitation, he vowed he would once again be hiking on the rustic trails above his home.

Today Mr. Tull, 63, drives his own car, sometimes takes over the controls of a private plane, and goes on an annual trout-fishing trip to Colorado with friends. But he has not been able to hike that trail.

“That is one of the things I miss most,” Mr. Tull, now retired and receiving a disability pension, said in a telephone interview from his home. “Every single hour of every single day, the plague affects our lives, but about the only time I really get angry these days is when, because of my physical condition, there is something I want to do but can’t.”

He has appeared in several television documentaries, speaking to medical researchers around the world and dealing with a posse of journalists as his very private ordeal has been played out in public.

“Basically Lucinda and I surrendered our privacy to the press and the people who make documentaries,” Mr. Tull said. “But you know what? That didn’t bother us a bit. Lucinda had been an actress and I had been a trial lawyer. We were used to it.”

Ms. Marker, who has started to write about their ordeal, says that after 10 years she is coming to terms with it emotionally and psychologically. Yet many aspects of their case still puzzle medical experts.

In particular, no one knows why she was so easily cured while he nearly died.

Bubonic plague is transmitted by fleas that feed off pack rats, ground squirrels and prairie dogs in the mountains of New Mexico and several other states. According to the Centers for Disease Control and Prevention, the disease probably came to the United States around 1900, in Asian rats that escaped from ships in the port of San Francisco.

Initially, plague was restricted to cities. The worst outbreak came in 1907, after the San Francisco earthquake. Vermin control programs prevented further outbreaks, but fleas hitched onto other animals in the wild.

Dr. Paul Ettestad, public health veterinarian for the New Mexico Department of Health, said prairie dogs became an “amplification host,” carrying the disease to their burrows and spreading it throughout their territory. Today, the easternmost limit of the plague roughly corresponds to the 100th meridian, which passes through central Texas. Known as the plague line, is it also the extent of the prairie dog population.

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